Medications, in order of preference include:
1. The organophosphates, which imply some risk to the fish being treated.
2. The formalin containing compounds, which are famed for their effectiveness, but also their ability to burn fish and kill filters.
3. Mixtures of organophospates and insecticides, a group most prominently represented by "Fluke Tabs". This compound contains carbonate insecticide.
4. Praziquantel, which is too expensive for use in ponds, but works nicely in tanks.
5. Last choice compounds would include potassium permanganate, copper, and maybe others. This last choice class is dangerous, to say the least and should be reserved for professional fisheries personnel.
Impediments to treatment with Organophosphates include:
1. The minimum dose is 0.25 PPM but this should be increased in harder water or water with a lot of carbonate alkalinity or a correspondingly higher pH. Organophophates are bound by carbonates. Used in systems with a pH over 7.4, a hardess over 30 PPM or a total alkalinity over 80 PPM, the compounds need to be used at double and in some cases, based only on serial microscopy, quadrupled strength, to achieve a level that can influence the fluke population. Increases involve two different modifications of either amount or interval, including possible double or triple dosing at .5 PPM or .75 PPM or using the drug twice as frequently.
2. Cold water make organophosphates less safe because the fish do not metabolize the compounds as well as in warmer water. I have treated fish in 55F (springtime) water and seen them go corkscrewing. This is a reversible sign, simply by either changing out some of the water, warming the fish in a holding facility or simply suspending treatment and allowing the fish to revive.
3. Very warm water, over 80F permits the drug to be absorbed far too fast, and at regular dosing intervals, the fish become intoxicated as well.
The Formalin Compounds may Fail:
1. Formalin compounds sink in cooler water and are very hard to disperse for good effect.
2. Formalin is bound by organics so in dirty systems, levels of formalin may not remain high enough to kill adult flukes and intercept emerging larvae.
3. Oxygen consumption by the formalin compounds leaves caustic areas on the surface of the fish and destruction of precious filter bacteria are also hazards of its use.
Formalin is basically Formaldehyde in water. The most common is 37%. Unfortunately, most commonly available preparations contain some Methanol, which contributes heavily to the compound's toxicity to smaller fish. An important point to consider when using Formalin in fresh water systems is that the compound uses or binds free oxygen in systems and the following rule applies: for every 5mg/l (PPM) of Formaldehyde, 1 PPM free oxygen will be used. Formalin's primary use would be only in the treatment of Saprolegnia, (fungus) or Gill Flukes that had not responded to salt. The only other time to use Formalin is if the plants, which might be harmed by salt are more important than the fish. Formalin is used most effectively as a continuous treatment by adding 1cc per 10 gallons water, directly to the system. The most effective way to add it is to drop the water level to half of the pond's volume, then add the amount of Formalin that was calculated for the entire volume. Dump in the calculated amount, wait 2 hours and then top off the pond. You could do a 30 - 40% water change 2 days later and re-apply at full dose using the same drain, treat and top off method. Then repeat 2 - 3 days again, after a 30-40 % water change. A study done in 1976 suggests that Formalin will kill off a substantial portion of your nitrifying bacteria, causing water quality deterioration, in addition to the losses of Oxygen.
Fluke Tabs must be dosed high enough and long enough. Here again, in cool water, the parasites move through their life cycles slowly, so it is important to blanket the system and leave in medication long enough to intercept the emerging larvae. Praziquantel is expensive, but it is also effective.
Praziquantel (trade name - Droncit) is available in a cat and dog form from the Vet. You simply add 2 - 3 PPM to the tank you are deworming.